KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CSNK1E
All Species:
15.76
Human Site:
S354
Identified Species:
26.67
UniProt:
P49674
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P49674
NP_001885.1
416
47315
S354
P
V
A
S
T
P
A
S
R
I
Q
P
A
G
N
Chimpanzee
Pan troglodytes
XP_515128
385
44007
S323
R
M
G
Q
L
R
G
S
A
T
R
A
L
P
P
Rhesus Macaque
Macaca mulatta
XP_001113761
317
36681
R256
A
T
Y
L
N
F
C
R
S
L
R
F
D
D
K
Dog
Lupus familis
XP_850168
416
47320
S354
P
T
A
S
T
P
A
S
R
I
Q
Q
A
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JMK2
416
47304
S354
P
V
A
S
T
P
A
S
R
I
Q
Q
T
G
N
Rat
Rattus norvegicus
P97633
325
37477
R264
A
M
Y
L
N
Y
C
R
G
L
R
F
E
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLL1
416
47453
S354
P
M
A
S
T
P
T
S
R
I
Q
Q
S
G
N
Frog
Xenopus laevis
Q5BP74
415
47421
T347
V
T
P
S
T
P
L
T
P
T
S
H
T
A
N
Zebra Danio
Brachydanio rerio
Q6P3K7
409
46813
P347
A
P
P
T
P
L
T
P
T
S
H
T
A
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76324
440
47939
A354
G
G
G
G
G
S
A
A
Q
Q
Q
L
Q
G
G
Honey Bee
Apis mellifera
XP_395574
413
47530
V345
Q
C
L
A
N
I
S
V
G
T
V
G
P
T
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_779963
435
49455
V354
P
A
A
V
V
N
P
V
A
V
G
G
F
H
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42158
450
50928
S372
R
D
S
M
I
P
S
S
S
L
F
A
Q
S
A
Baker's Yeast
Sacchar. cerevisiae
P29295
494
57322
L370
E
I
K
Q
Q
T
I
L
N
N
N
A
A
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.5
72.5
99.2
N.A.
98.8
56.9
N.A.
N.A.
97.3
84.3
84.3
N.A.
62.7
67.5
N.A.
67.5
Protein Similarity:
100
92.5
75
99.2
N.A.
99
65.8
N.A.
N.A.
98.5
88.4
88.6
N.A.
72.9
77.4
N.A.
75.4
P-Site Identity:
100
6.6
0
86.6
N.A.
86.6
0
N.A.
N.A.
73.3
26.6
6.6
N.A.
20
0
N.A.
13.3
P-Site Similarity:
100
20
13.3
86.6
N.A.
86.6
20
N.A.
N.A.
86.6
33.3
13.3
N.A.
33.3
13.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
56.6
46.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
70
63.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
8
36
8
0
0
29
8
15
0
0
22
29
8
22
% A
% Cys:
0
8
0
0
0
0
15
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
0
0
0
0
0
0
0
8
8
0
% D
% Glu:
8
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
8
15
8
0
0
% F
% Gly:
8
8
15
8
8
0
8
0
15
0
8
15
0
36
8
% G
% His:
0
0
0
0
0
0
0
0
0
0
8
8
0
8
0
% H
% Ile:
0
8
0
0
8
8
8
0
0
29
0
0
0
0
0
% I
% Lys:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
8
% K
% Leu:
0
0
8
15
8
8
8
8
0
22
0
8
8
0
0
% L
% Met:
0
22
0
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
22
8
0
0
8
8
8
0
0
8
36
% N
% Pro:
36
8
15
0
8
43
8
8
8
0
0
8
8
8
8
% P
% Gln:
8
0
0
15
8
0
0
0
8
8
36
22
15
0
0
% Q
% Arg:
15
0
0
0
0
8
0
15
29
0
22
0
0
0
0
% R
% Ser:
0
0
8
36
0
8
15
43
15
8
8
0
8
15
8
% S
% Thr:
0
22
0
8
36
8
15
8
8
22
0
8
15
8
8
% T
% Val:
8
15
0
8
8
0
0
15
0
8
8
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
15
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _